Percorso

Torch IgM

The device code TORCHM.CE is intended to be used for the first screening of women in pregnancy, and in other “risk patients” in order to point out those samples that are positive for IgM to any of the TORCH infectious agents
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Description
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The device code TORCHM.CE is intended to be used for the first screening of women in pregnancy, and in other “risk patients” in order to point out those samples that are positive for IgM to any of the TORCH infectious agents (Toxoplasma gondii, Rubella virus, Cytomegalovirus and Herpes Simplex virus). In case the assay turns out to be positive, the clinician then on such patient will go throughout specific TORCH tests able to determine which TORCH pathogen is involved in the infection. For “in vitro” diagnostic use only. TORCH microorganisms are ubiquitous human pathogens, whose infections continue to be an important health problem in certain patient populations, such as pregnant women, newborns, graft recipients of solid organs or bone marrow, and AIDS patients. In these last groups, Toxoplasma and CMV are a major cause of morbidity and mortality.

The screening of TORCH specific IgM antibodies, even if does not indicate which microorganism is involved, is of great value in the first diagnosis of acute/primary infections or reactivation of a latent one, particularly in the absence of typical clinical symptoms, as usually happens for CMV and for Toxoplasma. Recently developed IgM capture ELISA’s for TORCH, taking advantage of specific synthetic antigens or highly purified native ones, provide the clinician with an highly specific and reliable diagnostic test, not affected by Rheumatoid Factor, for the monitoring of such “risk” populations.

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