Enzyme Immuno Assay (ELISA) for the determination of IgM antibodies to Coxsackievirus B (CoxB) in human plasma and sera. For “in vitro” diagnostic use only. Coxsackievirus belongs to a group of viruses called enteroviruses and are present in two main groups, A and B. Most Coxsackievirus infections are not serious. They typically cause only mild signs and symptoms, such as fever, rash, sore throat, joint pain and headache. Symptoms usually last about a week. Coxsackievirus infection occurs most often in young children. Group A viruses are associated with aseptic meningitis, colds, acute hemorrhagic conjunctivitis and acute myocardiopathies and group B are associated with acute myocarditis and a polio-like paralysis.