Enzyme ImmunoAssay (ELISA) for the determination of IgG antibodies to Yellow Fever Virus (YFV) in human plasma and sera coming from naturally infected people and vaccinated subjects to monitor the presence of protective IgG.

Yellow Fever virus is an RNA Flavivirus of the family of Flaviviridae transmitted by the mosquito “Aedes Aegypti”, causing a severe infection in humans, quite often lethal if not immediately treated. Since many years a very efficient vaccine has been available and widely used to protect people living in endemic regions and travelers.
Diagnosis of YFV natural infection and follow-up of vaccination is generally obtained through detection of virus-specific IgG antibodies by means of ELISA techniques.